Search results for " essential thrombocythemia"

showing 3 items of 3 documents

Differential diagnostic features of bone marrow biopsies in essential thrombocythemia

2004

Essential Thrombocythemia (ET) is a chronic myeloproliferative disorder (CMPD) characterized by a high platelet count and originating from a multipotent stem cell. For a long time, according to Polycythaemia Vera Study Group (PVSG) criteria, ET diagnosis has not included histopathological data. Bone Marrow (BM) histology was used only to exclude previous or other subtypes of Ph-CMD or Myelodysplastic syndromes (MDS). In addition, the lack of any cytogenetic or molecular-biological marker has made the discrimination between ET and cases of Reactive Thrombocytosys (RT) without a well known cause quite problematic. Analogously, the distinction of ET from the other Ph- CMPDs with similar clinic…

Classification essential thrombocythemia image segmentation wavelet analysis.Settore INF/01 - Informatica
researchProduct

Splenomegaly Impacts Prognosis in Essential Thrombocythemia and Polycythemia Vera: A Single Center Study

2019

Splenomegaly is one of the major clinical manifestations of primary myelofibrosis and is common also in other chronic Philadelphia-negative myeloproliferative neoplasms, causing symptoms and signs and affecting quality of life of patients diagnosed with these diseases. We aimed to study the impact that such alteration has on thrombotic risk and on the survival of patients with essential thrombocythemia and patients with Polycythemia Vera (PV). We studied the relationship between splenomegaly (and its grade), thrombosis and survival in 238 patients with et and 165 patients with PV followed at our center between January 1997 and May 2019.

Pediatricsmedicine.medical_specialtySingle CenterArticle03 medical and health sciences0302 clinical medicinePolycythemia veraQuality of lifehemic and lymphatic diseasesmedicineMyelofibrosisPolycythemia VeraThrombotic riskessential thrombocythemiaEssential thrombocythemiabusiness.industrylcsh:RC633-647.5Hematologylcsh:Diseases of the blood and blood-forming organsmedicine.diseaseThrombosis030220 oncology & carcinogenesisSplenomegalysplenomegaly; polycythemia vera; essential thrombocythemiabusiness030215 immunologyHematology Reports; Volume 11; Issue 4; Pages: 8281
researchProduct

European Bone Marrow Working Group trial on reproducibility of World Health Organization criteria to discriminate essential thrombocythemia from pref…

2012

Any study of myeloproliferative neoplasms (MPNs) that lacks adequate clinical input is doomed to cause diagnostic uncertainty and increased controversy. In the paper by Buhr et al. published in Haematologica,[1][1] the authors studied 102 cases of essential thrombocythemia (ET) and early primary

WHO classificationPathologymedicine.medical_specialtyGroup trialPediatricsessential thrombocythemiaEssential thrombocythemiabusiness.industryMEDLINEmyelofibrosisHematologySettore MED/08 - Anatomia Patologicamedicine.diseaseWorld healthmedicine.anatomical_structuremedicineWHO classification; early primary myelofibrosis; essential thrombocythemiaearly primary myelofibrosiBone marrowMyelofibrosisWho classificationbusiness
researchProduct